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Prostate Cancer

Prostate Cancer Care at UVM Cancer Center

Prostate cancer — which forms in the prostate gland of the male reproductive system — is the most common type of cancer in men. Many prostate cancers grow slowly and pose little risk, and some may not even require treatment. Other forms of prostate cancer can be more aggressive and spread quickly to other areas of the body.

At University of Vermont Health, you receive advanced prostate cancer care from trusted experts. Our team provides a patient-centered approach that includes comprehensive, state-of-the-art treatment and support for you and your family. We develop a personalized prostate cancer treatment plan that may include multiple therapies. You also have access to clinical trials only available at select cancer centers nationwide.

A medical provider speaks with a patient.

Why Choose UVM Health?

As a leading cancer program in the region, we offer:

  • Advanced technology: We use diagnostic and treatment technology not widely available in the region. Our diagnostic radiology department is among a select few in the region offering prostate-specific membrane antigen (PSMA) PET scan, which can more accurately and painlessly identify prostate tumors.
  • Minimally invasive procedures: If you need surgery to remove your prostate (prostatectomy), you may be eligible for robot-assisted surgery. This method uses precise robotic technologies and small incisions to remove the prostate, leading to a faster recovery with less pain and fewer complications.
  • Innovation: As part of a health system anchored by an academic medical center, our physicians are active researchers and participate in prestigious cancer research groups, such as the SWOG Cancer Research Network and NRG Oncology, that lead groundbreaking clinical trials. Through this participation, we are able to offer additional care options for difficult-to-treat cancers.
  • Convenience: Our network of providers gives you access to leading-edge cancer care throughout the region. Whenever possible, we schedule your appointments with multiple members of your care team on the same day.

Prostate Cancer Symptoms

In its early stages, prostate cancer often causes no symptoms. As the tumor grows larger, it may cause symptoms such as:

  • Blood in the urine or semen
  • Frequent urination, especially at night
  • Pain during ejaculation
  • Problems getting and maintaining an erection
  • Difficulty urinating, including trouble starting urination, weak urine flow or painful urination
  • Stiffness or pain in the lower back, hips or pelvis

Prostate Cancer Screening

Prostate cancer screening is one of many cancer screenings offered at UVM Cancer Center. It involves a blood test to check your levels of prostate-specific antigen (PSA). A higher-than-expected PSA can be a sign of prostate cancer, but not always. Also, not everyone with elevated PSA and prostate cancer needs treatment. Talk with your primary care provider to learn more about whether prostate cancer screening is right for you.

Prostate Cancer Diagnosis

If your doctor suspects that you may have prostate cancer, they will order a series of evaluations and tests to confirm the diagnosis and determine a prognosis. These may include:

Imaging Tests for Prostate Cancer

Tests such as CT, MRI, PET and bone scans help us identify prostate cancer and determine whether it has spread to surrounding tissues. Our radiologists are highly trained to interpret these images.

Biopsy for Prostate Cancer

A biopsy is a procedure to take a tissue sample from the prostate for examination. A specialist in diagnosing cancer (pathologist) looks at the tissue under a microscope to confirm or rule out a prostate cancer diagnosis.

Prostate-Specific Membrane Antigen (PSMA) PET Scans

This highly sensitive test detects proteins that occur in some prostate tumors and helps us pinpoint the precise location of those tumors. PSMA PET is an important test for people who have a high risk of cancer spreading or have cancer that comes back after treatment. This test is not widely available in the region.

Tumor Genetic Testing for Prostate Cancer

In some cases, genetic testing for cancer helps us pinpoint genetic features of a tumor that determine your eligibility for certain treatments.

Family Genetic Testing for Prostate Cancer

Your doctor may recommend genetic testing for you and your family if you:

  • Are diagnosed with prostate cancer at a young age
  • Have a family history of prostate cancer or other related cancers, such as breast and ovarian cancer
  • Have prostate cancer that has spread outside the prostate

Our compassionate genetic counselors can find out if cancer-causing genes run in your family. They can also help you and your family understand your cancer risk.

Prostate Cancer Treatment

Not all people with prostate cancer need treatment. If you have early-stage cancer, your doctor may recommend a watch-and-wait approach to monitor you closely for any changes. If you need treatment, we create a personalized care plan based on your medical needs and personal preferences.

Our nurse navigators are available to support you throughout your treatment. They coordinate appointments, answer questions and guide you through every step.

Common treatments for prostate cancer include:

Prostatectomy

Radical prostatectomy is the removal of the entire prostate. It is an option for prostate cancer that has not spread to other areas of your body. We use minimally invasive robotic surgery for prostatectomies whenever possible to reduce healing time and get you back to your daily life more quickly.

Radiation Therapy for Prostate Cancer

Radiation therapy is an alternative to surgery for cancer that has not spread beyond the prostate. We use methods that deliver high doses of radiation therapy in less time, such as intensity modulated radiation therapy (IMRT) and stereotactic body radiation therapy (SBRT).

IMRT and SBRT tailor radiation beams to the tumor’s exact shape. These technologies reduce treatment from nine weeks to four weeks (IMRT) or sometimes five days (SBRT), depending on your condition. We are the only site in Vermont that offers prostate SBRT.

Your care may also include:

  • Hydrogel rectal spacer: Is a small liquid pouch your doctor inserts between the prostate and rectum. The spacer protects the rectum from the effects of radiation.
  • Image guided radiation therapy (IGRT): Uses CT or ultrasound images to guide the delivery of radiation, including IMRT or SBRT

Some types of radiation therapy are available at sites throughout UVM Health. Specialists at University of Vermont Medical Center often make initial radiation therapy plans and collaborate with local physicians to deliver your care.

Androgen Deprivation Therapy

Androgens (male sex hormones) fuel prostate cancer cell growth. Androgen deprivation therapy (also called hormone therapy) helps slow this process. This treatment is often combined with radiation therapy as an initial treatment or to help control prostate cancer that comes back after surgery or has spread beyond the prostate.

Medical Oncology for Prostate Cancer

Medical oncology treatments are available for cancer that has spread outside the prostate, doesn’t respond to initial treatment or returns after treatment. They include:

  • Hormonal therapy: Lowers levels of male hormones to slow cancer growth
  • Immunotherapy: Directs your immune system to destroy cancer cells
  • Radiopharmaceutical therapy, such as Lutetium-177 (Pluvicto™): Combines a radioactive element with a molecule that attaches to a protein on the tumor cell (such as PSMA). The radioactivity destroys the tumor cell.
  • Targeted therapy: Binds to certain molecules on the surface of cancer cells and attacks the cells
  • Chemotherapy: Medications that destroy cancer cells
Cryotherapy for Prostate Cancer

This treatment applies extreme cold to prostate tissue, destroying cancer cells and their ability to multiply. Cryotherapy may be an option if you are not eligible for other therapies or if cancer comes back after treatment.

Prostate Cancer Clinical Trials

Clinical trials are a routine part of care team discussions. Participation in a clinical trial can give you access to new care methods years before they are widely available and is always voluntary.

Our multidisciplinary team of prostate cancer specialists participate in cooperative group, industry and investigator-led studies. If you are eligible for a specific trial, your provider will explain the benefits and risks of participating and the next steps for enrollment.

Cancer Care

Clinical Trials 

The UVM Cancer Center supports more than 100 active clinical trials focused on prevention, screening, treatment, supportive care and survivorship.  

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