Skip to main content
Login to MyChart

Help us elevate and expand our care, make breakthroughs in biomedical science and improve community health and wellness.

Donate today

Search UVM Health

Melanoma and Other Skin Cancers

Melanoma and Skin Cancer Care at UVM Cancer Center

University of Vermont Health offers leading-edge skin cancer care across Vermont and northern New York in a supportive and caring environment. As a patient, you have access to some of the world's premier specialists in the screening, diagnosis and treatment of skin cancer.

Patients and referring providers regularly turn to us for our expertise with difficult-to-treat skin cancers — our team successfully cares for some of the region’s most complex cases. We also offer advanced options for cancers that spread rapidly or recur (come back after treatment).

A medical provider shines a light on a patient's face during a skin check.

Why Choose UVM Health?

As a leading cancer program in the region, we offer:

  • An expert team: Our expert skin care specialists work alongside experienced surgeons, medical oncologists, radiation oncologists and pathologists to deliver advanced, comprehensive skin cancer care with compassion. As part of a health system anchored by an academic medical center, our physician-leaders are also researchers, many of whom train the next generation of experts.
  • Innovation: Many of our specialists are active researchers and lead clinical trials, giving you access to new treatments that may not be widely available. Current research includes methods for treating cancer with effective but less intense therapies and optimizing the timing of different therapy options. Researchers are also looking into novel drug combinations to activate the patient’s own immune system to attack their cancer.
  • Advanced treatments: Our specialists are experts in the full range of skin cancer treatments, including advanced techniques that improve outcomes. When skin cancer occurs in highly visible areas, such as the face, scalp and chest, our team removes it with precise techniques that minimize changes to your appearance.
  • Convenience: Our network of providers gives you access to some skin cancer services in clinic locations throughout the region. Out of respect for your time, we schedule your appointments with multiple members of your care team on the same day whenever possible.

Types of Skin Cancer

There are many types of skin cancer. Our team of specialists is experienced in treating both rare and more common skin cancers, including:

  • Basal cell carcinoma: The most common form of skin cancer, this usually slow-growing cancer develops in the basal cells, which produce new skin cells as old ones die. It typically occurs on areas of the skin exposed to the sun (such as the face and neck). If left untreated, it can cause local damage to tissues but rarely spreads to other areas of the body.
  • Squamous cell carcinoma: The second most common type of skin cancer, squamous cell carcinoma develops in the upper skin layers. It is most often caused by UV exposure and can occur anywhere on the body. While not usually life-threatening, it can grow rapidly and spread to other areas of the body.
  • Melanoma: This aggressive skin cancer develops in melanocytes, the cells that give skin its color. It can occur anywhere on the body and is likely to spread (metastasize) if not caught early.
  • Merkel cell carcinoma: This fast-growing cancer usually appears on the face and neck. It is much more likely to spread to other parts of the body and recur than other skin cancers.

Diagnosing Melanoma and Skin Cancer

If your provider suspects you may have skin cancer, they will perform a comprehensive evaluation. Your diagnosis may include advanced tests, some of which are not widely available elsewhere in the area.

Tests used to diagnose skin cancer include:

  • Biopsy: During a biopsy, your provider takes a tissue sample from the skin. A dermatopathologist examines the sample under a microscope to identify cancer cells. We may also biopsy a nearby lymph node to determine whether cancer has spread.
  • Imaging studies: For advanced skin cancers, your provider may order one or more imaging tests, such as an ultrasound, CT, MRI or positron emission tomography (PET). PET/CT scans are sophisticated tests that use a small amount of a radioactive substance injected into a vein to show abnormal cell activity.

Melanoma and Skin Cancer Treatment

Most skin cancer can be treated with in-office procedures such as Mohs micrographic surgery, which removes cancer layer by layer. Complex melanoma and other advanced skin cancers may require evaluation for more intensive therapies.

At UVM Health, you receive a personalized care plan. Throughout your cancer journey, our nurse navigators are by your side with support, coordinating appointments, answering questions and guiding your care.

Melanoma and Skin Cancer Surgery

Our experienced Mohs surgeons and general surgeons use precise techniques to remove cancers in highly visible areas while preserving your skin’s appearance and function. For complex cases, we work alongside skilled reconstructive surgeons and head and neck surgeons to protect your appearance.

Medical Oncology for Melanoma and Skin Cancer

Our medical oncologists work as a part of a team that specializes in treating advanced melanoma and skin cancer using medications that go through the entire body to fight cancer (systemic therapy).

You have access to numerous medical therapies, including newly approved options for skin cancers that spread rapidly or come back after treatment. Medical oncology therapies we offer include:

  • Immunotherapy drugs that enhance your own immune system to fight cancer, such as the injectable cancer vaccine, T-VEC
  • Targeted therapy drugs that destroy cancer cells with a specific genetic mutation
Skin Cancer Radiation Therapy

Radiation therapy can be an effective treatment for skin cancer, either alone or in combination with surgery and/or medical oncology drugs. Your doctor may recommend radiation if you cannot have surgery, to destroy cancer cells left behind after surgery, or if cancer recurs.

As part of our efforts to treat earlier-stage cancers with gentler methods, we may use radiation instead of surgery. Our specialists deliver radiation therapy using leading-edge technologies with the highest level of precision.

Melanoma and Skin Cancer Research

Our multidisciplinary team of specialists participate in industry, cooperative group and investigator-led studies that offer patients access to the latest care methods. While some studies are designed to improve cancer outcomes, we also have studies that help in the early detection and monitoring of cancer.

Participation in clinical trials is always voluntary. If you are eligible for a specific trial, your provider will explain the benefits and risks of participating and the next steps for enrollment.

Cancer Care

Clinical Trials 

The UVM Cancer Center supports more than 100 active clinical trials focused on prevention, screening, treatment, supportive care and survivorship.  

Two providers look at computer screen

Patient Resources

Locations Near You

View all locations

Share your location to see nearby providers and availability

844-UVM-HEALTH

Give to a Healthier Future

Help us elevate and expand our care, make breakthroughs in biomedical science and improve community health and wellness.

Healthier communities. Healthiest lives. Together.

University of Vermont Medical Center

111 Colchester Ave
Burlington, VT 05401

802-847-0000

Golisano Children's Hospital

111 Colchester Ave
Burlington, VT 05401

802-847-0000

Central Vermont Medical Center

130 Fisher Road
Berlin, VT 05602

802-371-4100

Champlain Valley Physicians Hospital

75 Beekman Street
Plattsburgh, NY 12901

518-561-2000

Elizabethtown Community Hospital

75 Park Street
Elizabethtown, NY 12932

518-873-6377

Alice Hyde Medical Center

133 Park Street
Malone, NY 12953

518-483-3000

Porter Medical Center

115 Porter Drive
Middlebury, VT 05753

802-388-4701

Home Health & Hospice

1110 Prim Road
Colchester, VT 05446

802-658-1900

© 2026 University of Vermont Health
Jump back to top