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Migraine Research Studies

Clinical trials are essential to helping us understand and find more effective treatments for health conditions, and allow participants to access treatments not available anywhere else.

The University of Vermont Medical Center is currently running two separate clinical trials to study migraines and their effects on the body. We are currently looking for paid volunteers for both studies.

If you experience migraine and meet the criteria listed below, you may be eligible to participate.

To learn more about research at the UVM Medical Center, please visit our clinical trials page.

One-Sided Migraine Study

As part of a research study to examine what is happening in the brain during a one-sided migraine attack, investigators at the UVM Headache Clinic are looking for volunteers with migraine who:

  • Are at least 18 years old
  • Experience one-sided migraine attacks
  • Have at least one day per month in which they are free of all migraine symptoms
  • Are able to undergo an MRI

If you choose to participate in this study, you would be asked to: 

  • Complete an MRI during a one-sided migraine (prior to taking pain relievers)
  • Complete a second MRI between attacks (when pain-free) and
  • Complete a cognitive and mood/anxiety assessment via Zoom tele-video

Each MRI takes approximately 1.5 hours and is performed at the UVM MRI Research Center; the Zoom tele-video takes 1 hour and is completed from home.

The key risk to participating in this study is prolonging a migraine attack, as you would need to withhold all pain relievers for your migraine scan

Subjects will be compensated $250 for their time and travel.

More Information

For more information, please contact study coordinators Olivia [dot] Nopatuvm [dot] edu (Olivia[dot]Nop[at]uvm[dot]edu) or ASenftmiatuvm [dot] edu (ASenftmi[at]uvm[dot]edu).