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Retroperitoneal Lymph Node Dissection for Testicular Cancer

Surgery Overview

Retroperitoneal lymph node dissection (RPLND) is surgery often used to treat testicular cancer. It is done to remove lymph nodes that may be cancerous from the lower back and pelvis.

During the early phases of stage I nonseminoma testicular cancer, it can be very difficult to tell whether these lymph nodes are cancerous without surgically removing them first. For this reason, RPLND may be done even though there is no sign that the cancer has spread (metastasized) beyond the testes.

For many people, the greatest risk associated with RPLND may be sexual side effects. Besides the risks related to any major surgery, RPLND also may lead to a condition known as retrograde ejaculation as a result of nerve damage caused by the surgery. In retrograde ejaculation, the semen flows from the prostate gland into the bladder rather than through the penis and outside the body, resulting in infertility. Those who suffer from retrograde ejaculation typically do not have erection problems or difficulty enjoying sex.

Nerve-sparing surgery techniques can prevent retrograde ejaculation in most people who have this surgery.

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Current as of: September 25, 2025

Author: Ignite Healthwise, LLC Staff

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This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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