Skip to main content
Login to MyChart

Help us elevate and expand our care, make breakthroughs in biomedical science and improve community health and wellness.

Donate today

Search UVM Health

Healthwise

Filler Injections

Filler injections are a cosmetic treatment used to smooth wrinkles or pitted scars in the skin, usually on the face. They are also used to make the lips fuller. When injected under the skin, a filler raises or puffs up that area. This usually goes away over time. There are many kinds of injectable fillers, including:

  • Hyaluronic acid (Restylane, Juvederm). The hyaluronic acid draws fluid to the treated area.
  • Fat cells harvested from your body (autologous fat).
  • Poly-L-lactic acid (Sculptra).
  • Calcium hydroxylapatite (Radiesse).
  • Microscopic plastic beads and bovine collagen (Bellafill). The plastic beads are made of poly(methyl methacrylate) (PMMA). The collagen goes away over time, but the plastic beads remain under the skin permanently.

Some doctors use fillers that are not approved by the U.S. Food and Drug Administration (FDA). Check with your doctor when deciding which treatment is right for you.

For some fillers, your skin is first numbed with a local anesthetic. Then a cosmetic surgeon or dermatologist uses a needle to inject the filler under the skin. A treatment session takes about 15 minutes. Some fillers are done in repeat sessions a couple of weeks apart.

What To Expect

After a filler injection, expect some pain, redness, swelling, and possibly itching. Swelling may last up to 36 hours. If symptoms start to get worse 1 to 3 days after the treatment, call your doctor. You may be getting an infection.

Why It Is Done

Filler injections are used to smooth scarred, wrinkled, or furrowed skin on the face. Some fillers are also used to add fullness to the lips.

How Well It Works

Depending on the area being treated, the filler, and your body's reaction to the filler, you might have one or more repeat injections.

Different fillers last different lengths of time. Slowly, your body absorbs the filler. This makes the skin go back to its normal state.

  • Hyaluronic acid (Restylane, Juvederm). The effect lasts about 6 to 12 months.
  • Fat cells harvested from your body (autologous fat). The effect can last for months to years.
  • Poly-L-lactic acid (Sculptra). The effect can last up to 2 years.
  • Calcium hydroxylapatite (Radiesse). The effect lasts about 12 months.
  • Microscopic plastic beads and bovine collagen (Bellafill). The effect has been shown to last for at least 5 years.

As with all cosmetic procedures, the results may or may not be what you hoped for.

Risks

Filler injection can lead to problems. Possible complications include:

  • Infection. Call your doctor if you have new redness, swelling, or pain after the first day. You may need antibiotics right away.
  • Bleeding or bruising. Before a filler injection, avoid alcohol use. If you take aspirin or some other blood-thinning medicine, be sure to talk to your doctor. Find out if you should stop taking it before your procedure. This includes any type of nonsteroidal anti-inflammatory drug (NSAID) or vitamin E.
  • Allergic reaction, such as rash, hives, swelling, or flu-like symptoms.
  • Lumpy skin surface after treatment.

There are rare reports of serious or life-threatening complications after filler injection, including anaphylactic shock, sepsis, blood clot in the retinal artery leading to blindness, skin breakdown (necrosis), and abscess needing drainage.

Credits

Current as of: September 24, 2025

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

© 2024-2025 Ignite Healthwise, LLC.

This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

844-UVM-HEALTH

Give to a Healthier Future

Help us elevate and expand our care, make breakthroughs in biomedical science and improve community health and wellness.

Healthier communities. Healthiest lives. Together.

University of Vermont Medical Center

111 Colchester Ave
Burlington, VT 05401

802-847-0000

Golisano Children's Hospital

111 Colchester Ave
Burlington, VT 05401

802-847-0000

Central Vermont Medical Center

130 Fisher Road
Berlin, VT 05602

802-371-4100

Champlain Valley Physicians Hospital

75 Beekman Street
Plattsburgh, NY 12901

518-561-2000

Elizabethtown Community Hospital

75 Park Street
Elizabethtown, NY 12932

518-873-6377

Alice Hyde Medical Center

133 Park Street
Malone, NY 12953

518-483-3000

Porter Medical Center

115 Porter Drive
Middlebury, VT 05753

802-388-4701

Home Health & Hospice

1110 Prim Road
Colchester, VT 05446

802-658-1900

© 2026 University of Vermont Health
Jump back to top