Skip to main content
Login to MyChart

Help us elevate and expand our care, make breakthroughs in biomedical science and improve community health and wellness.

Donate today

Search UVM Health

Health Library

Gilbert syndrome


You must carefully read the "Consumer Information Use and Disclaimer" below in order to understand and correctly use this information

What is Gilbert syndrome?

This is a condition that causes a substance called "bilirubin" to build up in the blood.

Gilbert syndrome is caused by an abnormal gene that runs in families. People who have Gilbert syndrome were born with it.

What are the symptoms of Gilbert syndrome?

Often, Gilbert syndrome does not cause any symptoms. If it does, the most common symptom is "jaundice." This makes the skin or whites of the eyes look yellow.

Symptoms usually first appear during the teen years, but they can also happen in newborn babies. In people with Gilbert syndrome, jaundice can be triggered by a fever, physical effort such as hard exercise, stress, or not eating.

Is there a test for Gilbert syndrome?

Yes. Your doctor or nurse can do different blood tests to see if you have Gilbert syndrome. In some cases, they can also order a test to check whether you have the gene that causes Gilbert syndrome. But the gene test is not usually needed.

How is Gilbert syndrome treated?

Gilbert syndrome does not need treatment. The jaundice does not usually cause health problems.

If you have Gilbert syndrome, tell all your doctors and nurses. Also tell them about all the medicines you take, including over-the-counter and herbal medicines. Your doctors and nurses need to know about your condition when picking medicines for you, because people with Gilbert syndrome can have worse side effects from certain medicines than other people.


Consumer Information Use and Disclaimer: Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider's examination and assessment of a patient's specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof.The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms. 2026© UpToDate, Inc. and its affiliates and/or licensors. All rights reserved.
Retrieved from UpToDate® Digital Architect on: April 21, 2026
Topic 17219 Version 14.0
844-UVM-HEALTH

Give to a Healthier Future

Help us elevate and expand our care, make breakthroughs in biomedical science and improve community health and wellness.

Healthier communities. Healthiest lives. Together.

University of Vermont Medical Center

111 Colchester Ave
Burlington, VT 05401

802-847-0000

Golisano Children's Hospital

111 Colchester Ave
Burlington, VT 05401

802-847-0000

Central Vermont Medical Center

130 Fisher Road
Berlin, VT 05602

802-371-4100

Champlain Valley Physicians Hospital

75 Beekman Street
Plattsburgh, NY 12901

518-561-2000

Elizabethtown Community Hospital

75 Park Street
Elizabethtown, NY 12932

518-873-6377

Alice Hyde Medical Center

133 Park Street
Malone, NY 12953

518-483-3000

Porter Medical Center

115 Porter Drive
Middlebury, VT 05753

802-388-4701

Home Health & Hospice

1110 Prim Road
Colchester, VT 05446

802-658-1900

© 2026 University of Vermont Health
Jump back to top