Skip to main content
Login to MyChart

Help us elevate and expand our care, make breakthroughs in biomedical science and improve community health and wellness.

Donate today

Search UVM Health

Health Library

Weight loss treatments


You must carefully read the "Consumer Information Use and Disclaimer" below in order to understand and correctly use this information

Am I at a healthy weight?

It depends on your height and your overall health.

Doctors use a measure called "body mass index," or "BMI," to help understand a person's weight. They use your weight and height to calculate your BMI (table 1). Based on this number, you fall into 1 of these categories:

  • Underweight – BMI under 18.5

  • Healthy weight – BMI between 18.5 and 24.9

  • Overweight – BMI between 25 and 29.9

  • Having obesity – BMI 30 or greater

Your doctor or nurse will often calculate your BMI at your medical appointments. But it's important to remember your weight and BMI are just 1 piece of your overall health. Someone with a lower BMI might not be healthy overall, and someone with a higher BMI can still be healthy.

How does my weight affect my health?

Having obesity increases the risks of many different health problems. It can also make it harder for you to move, breathe, and do other things people who are at a healthy weight can do easily.

People with obesity are more likely to get diabetes, heart disease, cancer, and lots of other health problems. They also tend to have shorter lifespans than people with a healthy weight. That's why it's important to try to keep your weight in a healthy range.

How can I lose weight?

You can start by talking to your doctor or nurse. They can help you make a plan to lose weight in a healthy way. They can also help you understand how many calories your body needs for energy. Losing weight takes work and can be hard, so it helps to have support.

The best weight loss plans help you have a healthy view of eating and exercise. With a good weight loss plan, many people can lose weight and keep it off. Reducing calories in your diet, burning calories through exercise, or both can help you lose weight:

  • Diet – There is no specific diet plan that works for everyone. Many "trendy" weight loss programs can end up being more harmful than helpful. Any diet that reduces how many calories you eat can help you lose weight, as long as you stick with it. You should try to find an eating pattern that works for you.

    It can also help to work with a dietitian (food expert). They can help you make healthy diet changes while making sure you get the nutrients your body needs.

  • Movement and exercise – Even gentle forms of exercise are good for your health. You can walk, dance, garden, or even just move your arms while sitting. For weight loss, the important thing is to increase how many calories you burn by moving more.

Combining a healthy diet with regular physical activity can help you get the best results. This is important even if your doctor recommends treatment for weight loss.

If you change your eating or exercise habits for a short time, you might lose weight. But you will regain the weight if you go back to your old habits. Weight loss is about changing your habits for the long term.

Can medicines help with weight loss?

Sometimes. Prescription weight loss medicines work by reducing your appetite or by changing how you digest food.

Your doctor might recommend medicine if you have not been able to lose weight in other ways, and you:

  • Have a BMI of 30 or greater, or

  • Have a BMI between 27 and 29.9 and also have weight-related medical problems, such as diabetes, heart disease, or high blood pressure

Your doctor might also prescribe medicine in other cases, such as if you carry extra weight in the belly area and have certain health conditions.

When doctors prescribe medicines for weight loss, they sometimes choose "GLP-1" medicines. This type of medicine was originally used for treating diabetes. But they can also help with weight loss in some people without diabetes. Examples include:

  • Tirzepatide (sample brand names: Zepbound, Mounjaro)

  • Semaglutide (sample brand names: Wegovy, Ozempic)

  • Liraglutide (sample brand name: Saxenda)

  • Orforglipron (brand name: Foundayo)

Most of these medicines come as shots that go under the skin. Some come as pills you take by mouth. They work by increasing the amount of insulin your body releases after eating. (Insulin is a hormone that helps control blood sugar.) They also slow digestion and make you feel full more quickly.

These medicines can work well for weight loss. But they can also cause side effects, like nausea, vomiting, diarrhea, and constipation. And they can be expensive. Most people have to keep taking these medicines long term. If you stop the medicine, you will likely gain back the weight you lost.

There are other medicines that can be used for weight loss, too.

Medicines can be a helpful part of treatment for some people. But even if your doctor does prescribe medicine, they will still recommend making lifestyle changes. This can help improve your overall health.

If you are interested in taking medicine to help you lose weight, talk with your doctor. They can help you understand your options.

Can I try herbal or non-prescription medicines to lose weight?

Be careful about non-prescription ("over-the-counter") products advertised to help with weight loss:

  • Many herbal weight loss medicines do not work, and some are unsafe. Check with your doctor or pharmacist before you take any herbal weight loss medicines.

  • There is also an over-the-counter version of a prescription medicine called orlistat (brand name: Alli). Even though you can get this medicine without a prescription, talk to your doctor before taking it. Orlistat can be a good option for some people, but it has risks. It can also cause unwanted side effects, such as cramps, burping, and gas.

  • Some weight loss medicines are sold over the internet. But they can contain harmful ingredients and can be unsafe.

How does weight loss surgery work?

It works by making you take in fewer calories. Surgery can do this in different ways, including reducing how much food you can eat, making you feel fuller faster, and changing the levels of hormones that affect your appetite. In some cases, such as with "gastric bypass," they can decrease the nutrients your body absorbs.

Weight loss surgery is appropriate only if you have not been able to lose weight in other ways, and if you:

  • Have a BMI above 35, or

  • Have a BMI above 30, and have a medical problem related to obesity, such as diabetes, heart disease, or high blood pressure

There are also weight loss procedures that can be done "endoscopically." This means the doctor does not make any cuts ("incisions") in the skin. Instead, they put a thin tube (called an "endoscope") into the mouth and then the stomach. Then, they use special tools at the end of the tube to do the procedure or insert a device. Examples include a "gastric balloon" and "endoscopic sleeve gastroplasty."

Each type of weight loss surgery is different, and each has different benefits and risks. If you are thinking about surgery, your doctor can talk to you about your situation and options. They can also talk to you about the risks and benefits of each type of surgery (table 2).

How do I decide if weight loss treatment is right for me?

If your doctor suggests weight loss treatment, ask these questions:

  • How much weight can I expect to lose, and how long will it take? – This depends on the treatment. Some weight loss medicines start working quickly, often within a few months. For surgery, the amount of weight loss and how long it takes depends on the specific procedure.

  • Will the weight loss from this treatment last? – Certain treatments, such as diet, exercise, and weight loss medicines, are only effective while they are used. People who stop weight loss medicines usually gain the weight back. Weight loss from surgery usually lasts the longest, because it changes how the body takes in food.

  • Will weight loss treatment improve my other medical conditions? – Many conditions that get worse with weight gain can also improve with weight loss. Common examples include type 2 diabetes, high blood pressure, high cholesterol, sleep apnea, fatty liver disease, and certain joint problems. Your doctor or nurse can help you decide which treatment is best for you based on your other medical conditions.

  • What are the risks of this treatment? – All weight loss medicines can cause side effects. All weight loss surgeries can lead to infection, bleeding, needing other procedures, and even death. For weight loss surgery, make sure your surgeon is very experienced and you are treated at a certified "Center of Excellence."

  • Which diet and lifestyle changes will I need to make? – Weight loss treatments are not "shortcuts" you can take to avoid making lifestyle changes. People must also change how they eat and how active they are. No single weight loss treatment works on its own. Sometimes, people can get surgery only after they lose some weight on their own through diet and exercise first. Working with a dietitian can help.

  • Will I be able to process food normally? – Some types of weight loss surgery leave people unable to get all the nutrients they need from food. After weight loss surgery, most people need to take vitamin and mineral supplements for the rest of their lives. You might need to take more supplements, depending on the procedure.

Images

table 1: How to find your BMI

 

Healthy weight

Overweight

Obesity

BMI (kg/m2)

19

20

21

22

23

24

25

26

27

28

29

30

35

40

Height (inches)

Weight (pounds)

58"

91

96

100

105

110

115

119

124

129

134

138

143

167

191

59"

94

99

104

109

114

119

124

128

133

138

143

148

173

198

60"

97

102

107

112

118

123

128

133

138

143

148

153

179

204

61"

100

106

111

116

122

127

132

137

143

148

153

158

185

211

62"

104

109

115

120

126

131

136

142

147

153

158

164

191

218

63"

107

113

118

124

130

135

141

146

152

158

163

169

197

225

64"

110

116

122

128

134

140

145

151

157

163

168

174

204

232

65"

114

120

126

132

138

144

150

156

162

168

174

180

210

240

66"

118

124

130

136

142

148

155

161

167

173

179

186

216

247

67"

121

127

134

140

146

153

159

166

172

178

185

191

223

255

68"

125

131

138

144

151

158

164

171

177

184

190

197

230

262

69"

128

135

142

149

155

162

169

176

182

189

196

203

236

270

70"

132

139

146

153

160

167

174

181

188

195

202

209

243

278

71"

136

143

150

157

165

172

179

186

193

200

208

215

250

286

72"

140

147

154

162

169

177

184

191

199

206

213

221

258

294

73"

144

151

159

166

174

182

189

197

204

212

219

227

265

302

74"

148

155

163

171

179

186

194

202

210

218

225

233

272

311

75"

152

160

168

176

184

192

200

208

216

224

232

240

279

319

76"

156

164

172

180

189

197

205

213

221

230

238

246

287

328

Body mass index, or "BMI," is a measure of weight in relation to height. Doctors use this calculation to help understand a person's health risks. Based on the number, a person falls into 1 of 4 categories: underweight, healthy weight, overweight, or obesity.

To calculate your BMI, find your height (in inches) on the left. Then, look at that row to find your weight (in pounds). The number at the top of that column is your BMI.

Graphic 83696 Version 3.0

table 2: Comparison of weight loss surgeries

 

Roux-en-Y gastric bypass

Gastric sleeve

SADI/DS

Endoscopic sleeve

How quickly will I lose weight?

Usually quickly

Less quickly

Very quickly

Gradually

Does it require surgery?

Yes

Yes

Yes

No

Does it require anesthesia?

Yes

Yes

Yes

Yes

Will my intestines be rerouted?

Yes

No

Yes

No

Will a device stay in my body?

No

No

No

No

Will I be able to return to my normal activities?

Yes

Yes

Yes

Yes

How much weight will I lose (total body weight)?*

30 to 35%

25 to 30%

40 to 45%

15 to 20%

Should I expect my other weight-related problems to improve?

Yes

Yes

Yes

Yes

What are the problems with the procedure?

Some patients may develop ulcers, bowel obstructions, and malnutrition

Some patients may develop bad reflux

Patients will have more frequent bowel movements

Not sure how long it will last

Is it safe?

Yes

Yes

Yes

Very safe

DS: duodenal switch; ESG: endoscopic sleeve gastroplasty; RYGB: Roux-en-Y; SADI: Single-anastomosis duodenal ileal bypass; SG: sleeve gastrectomy.
* Total body weight means what percentage of the total amount of weight loss. So, a 300 lb person would lose about 90 to 105 lbs with a RYGB, 75 to 90 lbs with an SG, 120 to 135 lbs with an SADI/DS, and 45 to 60 lbs with an ESG.

Graphic 73045 Version 17.0


Consumer Information Use and Disclaimer: Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider's examination and assessment of a patient's specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof.The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms. 2026© UpToDate, Inc. and its affiliates and/or licensors. All rights reserved.
Retrieved from UpToDate® Digital Architect on: October 20, 2026
This topic retrieved from UpToDate on: Sep 30, 2026.
844-UVM-HEALTH

Give to a Healthier Future

Help us elevate and expand our care, make breakthroughs in biomedical science and improve community health and wellness.

Healthier communities. Healthiest lives. Together.

University of Vermont Medical Center

111 Colchester Ave
Burlington, VT 05401

802-847-0000

Golisano Children's Hospital

111 Colchester Ave
Burlington, VT 05401

802-847-0000

Central Vermont Medical Center

130 Fisher Road
Berlin, VT 05602

802-371-4100

Champlain Valley Physicians Hospital

75 Beekman Street
Plattsburgh, NY 12901

518-561-2000

Elizabethtown Community Hospital

75 Park Street
Elizabethtown, NY 12932

518-873-6377

Alice Hyde Medical Center

133 Park Street
Malone, NY 12953

518-483-3000

Porter Medical Center

115 Porter Drive
Middlebury, VT 05753

802-388-4701

Home Health & Hospice

1110 Prim Road
Colchester, VT 05446

802-658-1900

© 2026 University of Vermont Health
Jump back to top