Health Library
Weight loss treatments
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Am I at a healthy weight?
It depends on your height and your overall health.
Doctors use a measure called "body mass index," or "BMI," to help understand a person's weight. They use your weight and height to calculate your BMI (figure 1). Based on this number, you fall into 1 of these categories:
Underweight – BMI under 18.5
Healthy weight – BMI between 18.5 and 24.9
Overweight – BMI between 25 and 29.9
Having obesity – BMI 30 or greater
Your doctor or nurse will often calculate your BMI at your medical appointments. But it's important to remember your weight and BMI are just 1 piece of your overall health. Someone with a lower BMI might not be healthy overall, and someone with a higher BMI can still be healthy.
How does my weight affect my health?
Having obesity increases the risks of many different health problems. It can also make it harder for you to move, breathe, and do other things people who are at a healthy weight can do easily.
People with obesity are more likely to get diabetes, heart disease, cancer, and lots of other health problems. They also tend to have shorter lifespans than people with a healthy weight. That's why it's important to try to keep your weight in a healthy range.
How can I lose weight?
You can start by talking to your doctor or nurse. They can help you make a plan to lose weight in a healthy way. They can also help you understand how many calories your body needs for energy. Losing weight takes work and can be hard, so it helps to have support.
The best weight loss plans help you have a healthy view of eating and exercise. With a good weight loss plan, many people can lose weight and keep it off. Reducing calories in your diet, burning calories through exercise, or both can help you lose weight:
Diet – There is no specific diet plan that works for everyone. Many "trendy" weight loss programs can end up being more harmful than helpful. Any diet that reduces how many calories you eat can help you lose weight, as long as you stick with it. You should try to find an eating pattern that works for you.
It can also help to work with a dietitian (food expert). They can help you make healthy diet changes while making sure you get the nutrients your body needs.
Movement and exercise – Even gentle forms of exercise are good for your health. You can walk, dance, garden, or even just move your arms while sitting. For weight loss, the important thing is to increase how many calories you burn by moving more.
Combining a healthy diet with regular physical activity can help you get the best results. This is important even if your doctor recommends treatment for weight loss.
If you change your eating or exercise habits for a short time, you might lose weight. But you will regain the weight if you go back to your old habits. Weight loss is about changing your habits for the long term.
Can medicines help with weight loss?
Sometimes. Prescription weight loss medicines work by reducing your appetite or by changing how you digest food.
Your doctor might recommend medicine if you have not been able to lose weight in other ways, and you:
Have a BMI of 30 or greater, or
Have a BMI between 27 and 29.9 and also have weight-related medical problems, such as diabetes, heart disease, or high blood pressure
Your doctor might also prescribe medicine in other cases, such as if you carry extra weight in the belly area and have certain health conditions.
When doctors prescribe medicines for weight loss, they sometimes choose "GLP-1" medicines. This type of medicine was originally used for treating diabetes. But they can also help with weight loss in some people without diabetes. Examples include:
Tirzepatide (sample brand names: Zepbound, Mounjaro)
Semaglutide (sample brand names: Wegovy, Ozempic)
Liraglutide (sample brand name: Saxenda)
Orforglipron (brand name: Foundayo)
Most of these medicines come as shots that go under the skin. Some come as pills you take by mouth. They work by increasing the amount of insulin your body releases after eating. (Insulin is a hormone that helps control blood sugar.) They also slow digestion and make you feel full more quickly.
These medicines can work well for weight loss. But they can also cause side effects, like nausea, vomiting, diarrhea, and constipation. And they can be expensive. Most people have to keep taking these medicines long term. If you stop the medicine, you will likely gain back the weight you lost.
There are other medicines that can be used for weight loss, too.
Medicines can be a helpful part of treatment for some people. But even if your doctor does prescribe medicine, they will still recommend making lifestyle changes. This can help improve your overall health.
If you are interested in taking medicine to help you lose weight, talk with your doctor. They can help you understand your options.
Can I try herbal or non-prescription medicines to lose weight?
Be careful about non-prescription ("over-the-counter") products advertised to help with weight loss:
Many herbal weight loss medicines do not work, and some are unsafe. Check with your doctor or pharmacist before you take any herbal weight loss medicines.
There is also an over-the-counter version of a prescription medicine called orlistat (brand name: Alli). Even though you can get this medicine without a prescription, talk to your doctor before taking it. Orlistat can be a good option for some people, but it has risks. It can also cause unwanted side effects, such as cramps, burping, and gas.
Some weight loss medicines are sold over the internet. But they can contain harmful ingredients and can be unsafe.
How does weight loss surgery work?
It works by making you take in fewer calories. Surgery can do this in different ways, including reducing how much food you can eat, making you feel fuller faster, and changing the levels of hormones that affect your appetite. In some cases, such as with "gastric bypass," they can decrease the nutrients your body absorbs.
Weight loss surgery is appropriate only if you have not been able to lose weight in other ways, and if you:
Have a BMI above 35, or
Have a BMI above 30, and have a medical problem related to obesity, such as diabetes, heart disease, or high blood pressure
There are also weight loss procedures that can be done "endoscopically." This means the doctor does not make any cuts ("incisions") in the skin. Instead, they put a thin tube (called an "endoscope") into the mouth and then the stomach. Then, they use special tools at the end of the tube to do the procedure or insert a device. Examples include a "gastric balloon" and "endoscopic sleeve gastroplasty."
Each type of weight loss surgery is different, and each has different benefits and risks. If you are thinking about surgery, your doctor can talk to you about your situation and options. They can also talk to you about the risks and benefits of each type of surgery (table 1).
How do I decide if weight loss treatment is right for me?
If your doctor suggests weight loss treatment, ask these questions:
How much weight can I expect to lose, and how long will it take? – This depends on the treatment. Some weight loss medicines start working quickly, often within a few months. For surgery, the amount of weight loss and how long it takes depends on the specific procedure.
Will the weight loss from this treatment last? – Certain treatments, such as diet, exercise, and weight loss medicines, are only effective while they are used. People who stop weight loss medicines usually gain the weight back. Weight loss from surgery usually lasts the longest, because it changes how the body takes in food.
Will weight loss treatment improve my other medical conditions? – Many conditions that get worse with weight gain can also improve with weight loss. Common examples include type 2 diabetes, high blood pressure, high cholesterol, sleep apnea, fatty liver disease, and certain joint problems. Your doctor or nurse can help you decide which treatment is best for you based on your other medical conditions.
What are the risks of this treatment? – All weight loss medicines can cause side effects. All weight loss surgeries can lead to infection, bleeding, needing other procedures, and even death. For weight loss surgery, make sure your surgeon is very experienced and you are treated at a certified "Center of Excellence."
Which diet and lifestyle changes will I need to make? – Weight loss treatments are not "shortcuts" you can take to avoid making lifestyle changes. People must also change how they eat and how active they are. No single weight loss treatment works on its own. Sometimes, people can get surgery only after they lose some weight on their own through diet and exercise first. Working with a dietitian can help.
Will I be able to process food normally? – Some types of weight loss surgery leave people unable to get all the nutrients they need from food. After weight loss surgery, most people need to take vitamin and mineral supplements for the rest of their lives. You might need to take more supplements, depending on the procedure.
Images
figure 1: Your body mass index (BMI)

Find your height (in feet and inches) in the top row. Then, find your weight (in pounds) in the first column. Now, find where the column for your height and the row for your weight meet. That is your BMI. For example, if you are 5-feet-9-inches tall and you weigh 260 pounds, your BMI is 38.
Graphic 62886 Version 4.0
| Roux-en-Y gastric bypass | Gastric sleeve | SADI/DS | Endoscopic sleeve |
|---|---|---|---|---|
How quickly will I lose weight? | Usually quickly | Less quickly | Very quickly | Gradually |
Does it require surgery? | Yes | Yes | Yes | No |
Does it require anesthesia? | Yes | Yes | Yes | Yes |
Will my intestines be rerouted? | Yes | No | Yes | No |
Will a device stay in my body? | No | No | No | No |
Will I be able to return to my normal activities? | Yes | Yes | Yes | Yes |
How much weight will I lose (total body weight)?* | 30 to 35% | 25 to 30% | 40 to 45% | 15 to 20% |
Should I expect my other weight-related problems to improve? | Yes | Yes | Yes | Yes |
What are the problems with the procedure? | Some patients may develop ulcers, bowel obstructions, and malnutrition | Some patients may develop bad reflux | Patients will have more frequent bowel movements | Not sure how long it will last |
Is it safe? | Yes | Yes | Yes | Very safe |
Graphic 73045 Version 17.0
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