Capsaicin for Osteoarthritis

Topic Overview

Capsaicin (Zostrix), available without a prescription, is a pain reliever that comes in a cream that you apply directly to your skin (topical analgesic). It has been found to relieve joint pain from osteoarthritis in some people when rubbed into the skin over affected joints.footnote 1 To be beneficial, the cream must be applied 3 or 4 times a day. And the effects may not be seen for several weeks.

The main ingredient in capsaicin is an extract from hot peppers. It appears to have no serious side effects. But some people may be allergic to capsaicin. The first time you use this topical cream, apply it to just a small area of skin to make sure there is no allergic reaction. Even people who are not allergic may notice a burning sensation. Some people may not be able to tolerate the discomfort associated with using capsaicin.

Related Information

References

Citations

  1. De Silva V, et al. (2011). Evidence for the efficacy of complimentary and alternative medicines in the management of osteoarthritis: A systematic review. Rheumatology, 50(5): 911–920.

Credits

Current as of: April 30, 2021

Author: Healthwise Staff
Medical Review: Anne C. Poinier MD - Internal Medicine
Martin J. Gabica MD - Family Medicine
Kathleen Romito MD - Family Medicine
Stanford M. Shoor MD - Rheumatology

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This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.